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KMID : 0374019830060010023
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Ewha Medical Journal
1983 Volume.6 No. 1 p.23 ~ p.27
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A Comparative Study on the Clinical Effects of Various Topical Corticosteroids by Psoriasis Plaque Test
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金鎭權/Kim, Jin Kwon
明基範/鞠泓一/Myung, Ki Bum/Kook, Hong Il
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Abstract
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The psoriasis´ plaque test; as a clinical and non-artificial model, provides information on the antiproliferative effect of topical corticosteroids, and it makes possible to evaluate various preparations simultaneously at a given time.
In this assay we compared the antiproliferative effects of six topical corticosteroids with occlusive dressing technique in fourteen psoriatic patients..
The results are summerized as follows
1) The psoriasis plaque test was an adequate method for evaluating antiproliferative effects of various corticosteroid preparations.
2) In contrast to prednisolone and triamcinolone acetonide, the effects of desoxymethasone, halcinonide, fluocinide, triamcinolone benetonide were evident, and the best of all was desoxymethasone.
3) No side effect developed during test period.
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